The short answer...we don't know. Theoretically possible, although you'd have to run them on different ports (obviously). You also would need to watch out for path collisions, i.e., files being written by both instances into the same directories, possibly with the same name. If you were to set REPLICATIONHOME in config.ini to different values for each instance, and run them out of separate paths so they could each have their own config.ini, it might very well work.